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Multiprofen-CC to Reduce Pain in Hand Arthritis
Sponsor: McMaster University
Summary
This clinical trial aims to find out if using 1 gram of Multiprofen-CC cream on the hands three times a day for 4 weeks can help reduce pain in adults with hand osteoarthritis, compared to a placebo (a cream with no active medicine). The research team will also look at how Multiprofen-CC affects hand function, opioid use, and how patients feel about their overall improvement. In addition, the research team will keep track of any side effects. Participants will: * Use both Multiprofen-CC and a placebo (a cream with no active medicine) during the study, in a random order. * Be asked to apply 1 gram of cream to their hands three times a day for 2 weeks, following the manufacturer's instructions. * Attend a visit before starting the study, after 2 weeks, and after 6 weeks. * Report any symptoms they experience during the study.
Official title: Multiprofen-CC to Reduce Pain in Hand Arthritis (MRP-HAND): A Crossover Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
42
Start Date
2026-01-01
Completion Date
2027-08-01
Last Updated
2026-01-07
Healthy Volunteers
No
Conditions
Interventions
Multiprofen-CC™ plus standard treatment
Standard care pain medications and topical Multiprofen-CC™ (1g TID) for 2 weeks
Placebo plus standard treatment
Standard care pain medications and visually identical topical placebo (1g TID) for 2 weeks
Locations (1)
St. Joseph's Healthcare Hamilton
Hamilton, Ontario, Canada