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Trigger Protocol on the Rate of Pregnancy After Intracytoplasmic Sperm Injection
Sponsor: Suez University
Summary
Infertility is a condition affecting both female and male, characterized by the inability to conceive after 12 months or more of regular, unprotected sexual activity. All over the world, over 186 million people are affected by this condition, with the majority living in developing countries. In developing countries, the prevalence of infertility among women of reproductive age is estimated to affect one in every four couples. Type of the trigger during intracytoplasmic sperm injection might has impact on pregnancy rate.
Official title: Impact of Trigger Protocol on the Rate of Pregnancy After Intracytoplasmic Sperm Injection: A Prospective Cohort Study
Key Details
Gender
FEMALE
Age Range
18 Years - 38 Years
Study Type
OBSERVATIONAL
Enrollment
90
Start Date
2025-05-01
Completion Date
2025-07-31
Last Updated
2025-05-13
Healthy Volunteers
No
Conditions
Interventions
Intracytoplasmic sperm injection
• All patients will commence controlled ovarian hyperstimulation (COH) on day 2 or 3 of their menstrual cycle. The initial treatment will be a daily administration of either highly purified human menopausal gonadotropin (hMG) or recombinant FSH (rFSH, Gonal-F 150 IU, Merck Serono, S.P.A, Italy) administered subcutaneously and intramuscularly for a duration of 10-12 days. The treatment will be continued until the final oocyte maturation. The starting dosage will be tailored based on the patient's age, antral follicle count (AFC), body mass index (BMI), serum FSH and AMH levels on days 2-3, as well as the patient's previous response to COH.
Locations (1)
faculty of medicine, Suez university
Suez, Egypt