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RECRUITING
NCT06966518
NA

Intraoperative Combination of Ketamine and Magnesium Sulfate Infusions on Postoperative Analgesia in Open Rhinoplasty

Sponsor: Ain Shams University

View on ClinicalTrials.gov

Summary

The study aims to evaluate the effectiveness of intraoperative combination of ketamine and magnesium sulfate infusions on postoperative analgesia in patients undergoing open rhinoplasty.

Official title: Effectiveness of Intraoperative Combination of Ketamine and Magnesium Sulfate Infusions on Postoperative Analgesia in Patients Undergoing Open Rhinoplasty: A Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2025-05-12

Completion Date

2025-10-01

Last Updated

2025-05-13

Healthy Volunteers

No

Interventions

DRUG

Ketamine and Magnesium Sulfate

Patients will receive a bolus of 0.5 mg/kg of ketamine given over a period of ten minutes followed by a constant infusion of 0.25 mg/kg/hr and a bolus dose of 30 mg/kg of magnesium sulfate during a 10-minute period followed by a continuous infusion of 9 mg/kg/hr.

DRUG

Saline 0.9%

Patients will receive saline 0.9% as a control group.

Locations (1)

Ain Shams University

Cairo, Egypt