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Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
Sponsor: Washington University School of Medicine
Summary
The investigation will establish biological plausibility and infrastructure required for a multisite clinical trial evaluating the re-purposing of fluvoxamine to mitigate postoperative delirium risk in geriatric patients undergoing non-cardiac non-intracranial surgery.
Official title: Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery (MD FluNCS)
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
46
Start Date
2026-03-07
Completion Date
2028-04-01
Last Updated
2026-02-27
Healthy Volunteers
No
Conditions
Interventions
Fluvoxamine
100mg Fluvoxamine Capsule 1. Day of surgery - Study drug to be taken morning of surgery and evening of surgery 2. Post-operative day 1 - Study drug to be taken morning and evening
Placebo
Placebo Capsule 1. Day of surgery - Study drug to be taken morning of surgery and evening of surgery 2. Post-operative day 1 - Study drug to be taken morning and evening
Locations (1)
Washington University School of Medicine/Barnes-Jewish Hospital
St Louis, Missouri, United States