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The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal Dystrophy
Sponsor: University Hospital Dubrava
Summary
The goal of this study is to learn if topical ROCK inhibitors protect endothelial corneal cells in patients with glaucoma and Fuchs endothelial corneal dystrophy after cataract surgery. The main question it aims to answer is: do topical ROCK inhibitors decrease the loss of corneal endothelial cells after cataract surgery? Researchers will compare topical ROCK inhibitor to a placebo (a look-alike substance that contains no drug) Participants will: Take topical ROCK inhibitor or a placebo every day for 4 weeks after cataract surgery and visit the clinic for checkups and tests.
Official title: The Effect of Topical Rho-kinase (ROCK) Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal Dystrophy (FECD)
Key Details
Gender
All
Age Range
40 Years - 90 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2025-04-01
Completion Date
2026-10-01
Last Updated
2025-05-14
Healthy Volunteers
No
Interventions
Netarsudil 0.02% Ophthalmic Solution
Topical Netarsudil 0.02% 1x daily for 30 days postoperatively
artificial tear substitute
Topical artificial tear substitute 1x daily for 30 days postoperatively.
Locations (1)
University Hospital Dubrava
Zagreb, Croatia