Clinical Research Directory
Browse clinical research sites, groups, and studies.
Prevention and Treatment of AKI VEXUS Guided Post Cardiac Surgery
Sponsor: Onassis Cardiac Surgery Centre
Summary
The main goal of this clinical trial is to learn if evaluation by ultrasound of venous congestion of liver and kidneys can guide treatment and prevent and treat acute kidney injury post cardiac surgery (CSA-AKI). Participants will: Be evaluated by liver and kidney veins ultrasound (treatment group) or a placebo post CSA-AKI. Fluid management for the treatment group will be based on a score that emerges from this evaluation (Venous Excess Ultrasound Score, VEXUS). Kidney function will be daily monitored and followed-up for 7 days and until discharge. Daily fluid balance and laboratory examination will be performed. Data will be recorded and collected and a statistical analysis will provide the results that will show or not a probable superiority of this evaluation comparing to the usual care.
Official title: Prevention and Treatment of Acute Kidney Injury After Cardiac Surgery Guided by Combined Cardiac and Splanchnic Sonographic Assessment
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
304
Start Date
2023-06-29
Completion Date
2025-10
Last Updated
2025-05-14
Healthy Volunteers
No
Interventions
VEXUS
Goal-directed fluid and drug therapy according to VEXUS measurements to minimize AKI
Locations (1)
Onassis Cardiac Surgery Center
Athens, Kallithea, Greece