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RECRUITING
NCT06972082
NA

Prevention and Treatment of AKI VEXUS Guided Post Cardiac Surgery

Sponsor: Onassis Cardiac Surgery Centre

View on ClinicalTrials.gov

Summary

The main goal of this clinical trial is to learn if evaluation by ultrasound of venous congestion of liver and kidneys can guide treatment and prevent and treat acute kidney injury post cardiac surgery (CSA-AKI). Participants will: Be evaluated by liver and kidney veins ultrasound (treatment group) or a placebo post CSA-AKI. Fluid management for the treatment group will be based on a score that emerges from this evaluation (Venous Excess Ultrasound Score, VEXUS). Kidney function will be daily monitored and followed-up for 7 days and until discharge. Daily fluid balance and laboratory examination will be performed. Data will be recorded and collected and a statistical analysis will provide the results that will show or not a probable superiority of this evaluation comparing to the usual care.

Official title: Prevention and Treatment of Acute Kidney Injury After Cardiac Surgery Guided by Combined Cardiac and Splanchnic Sonographic Assessment

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

304

Start Date

2023-06-29

Completion Date

2025-10

Last Updated

2025-05-14

Healthy Volunteers

No

Interventions

DEVICE

VEXUS

Goal-directed fluid and drug therapy according to VEXUS measurements to minimize AKI

Locations (1)

Onassis Cardiac Surgery Center

Athens, Kallithea, Greece