Clinical Research Directory

Inclusion Criteria: 1. Mandibular molar teeth with previous unsuccessful endodontic treatment from ≥ 1 year with asymptomatic apical periodontitis. 2. Teeth with inadequate obturation. 3. Teeth with broken instruments that can be bypassed and/or retrieved and not present in the apical third or passing through the apex. 4. Teeth with periapical lesion. 5. Patient with the ages of 18-65 years. 6. Patient medically healthy and free from systemic diseases or with mild controlled systemic disease. ASA I, II \* (52). 7. Patient with no acute pain or extraoral swelling. 8. Patients who agreed to participate in the study and attend the control visits. \- Exclusion Criteria: 1. Teeth requiring retreatment with a poor prognosis (root canal morphology altered, large carious cavity, internal or external root resorption, root perforation) 2. Teeth with vertical root fracture or open apex. 3. Patient with systemic disorders related to bone metabolism and using drugs that may affect bone metabolism. 4. Pregnant patients. 5. Patient under antibiotics treatment 2 weeks before the treatment. 6. Patients who could not attend follow up will be excluded from the study \-