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Non-Narcotic Pain Control After ACL Reconstruction
Sponsor: The Cleveland Clinic
Summary
This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narcotics (take zero oxycodone) after undergoing primary knee ACL reconstruction outpatient surgery.
Key Details
Gender
All
Age Range
15 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2025-07-15
Completion Date
2026-12-31
Last Updated
2025-08-11
Healthy Volunteers
No
Interventions
dispense of study drug
• Cohort Group 1 (Experimental): ketorolac 10mg with rescue medication oxycodone 5mg All patients will be given acetaminophen
Ketorolac
Patients will be randomized to either Ketorolac or Oxycodone
Locations (3)
Cleveland Clinic Coral Springs
Coral Springs, Florida, United States
Cleveland clinic sports medicine
Garfield, Ohio, United States
Cleveland Clinic
Strongsville, Ohio, United States