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CMV-associated Immunomodulation in Renal Transplant Patients
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
Cytomegalovirus (CMV) infection has been associated with an increased risk of bacterial, fungal and viral infections in solid organ transplant recipients. The purpose of this study to evaluate if the occurrence of CMV viremia modify the ability to develop optimal immune responses against other pathogens in kidney transplant recipients (heterologous immunity). The objective of this project is to identify the immune pathways affected by CMV in the context of immunosuppression associated with kidney transplantation.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-10-01
Completion Date
2029-10-01
Last Updated
2025-09-12
Healthy Volunteers
No
Conditions
Interventions
blood sampling
Blood samples will be taken at different timepoints following CMV viremia to evaluate the impact of CMV viremia over time.
Locations (4)
Hôpital Bicêtre
Le Kremlin-Bicêtre, France
Hôpital européen Georges Pompidou
Paris, France
Hôpital Necker-Enfants Malades
Paris, France
Insitut Pasteur
Paris, France