Clinical Research Directory

Inclusion Criteria: * Age \>18 years * Intravenous therapy with solutions requiring central vein cannulation (irritant drugs, extreme pH \<5 and \>9, osmolarity \> 600 mOsm/l), e.g., chemotherapy, parenteral nutrition with osmolarity \>900 mOsm/l * Difficult intravenous access with multiple blood collection * Ability to consent to participate in the study * Consent to participate in the study Exclusion Criteria: * Presence of central venous catheter, such as. centrally inserted central catheter or totally implanted vascular device * Indication of another type of vascular access device * Lack of veins suitable for cannulation of the arm * Infection, burns or other skin lesion on the upper extremities (involving the site of planned catheter insertion and attachment) * Pregnancy (confirmed by history and review of medical records or confirmed by positive human chorionic gonadotropin (hCG) determination in urine or plasma) * Lack of patient consent to participate in the study * Lack of capacity to consent to participate in the study * No physician present to supervise the procedure