Clinical Research Directory
Browse clinical research sites, groups, and studies.
Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia
Sponsor: Al-Azhar University
Summary
The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as regard number and severity.
Official title: Comparative Study Between Efficacy of Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression During General Anesthetic Emergence
Key Details
Gender
All
Age Range
21 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2025-06-02
Completion Date
2026-08-01
Last Updated
2025-06-11
Healthy Volunteers
No
Conditions
Interventions
Dexmedetomidine
Patients will receive 0.5 μg/kg dexmedetomidine in 10ml normal saline 10 min before the end of surgery.
Magnesium sulfate
Patients will receive 30 mg/kg IV magnesium sulfate 50% 10 min before the end of surgery.
Lidocaine
Patients will receive lidocaine 1.5 mg/kg lidocaine 10 min before the end of surgery.
normal saline
Patients will receive 10 ml normal saline 10 min before the end of surgery.
Locations (1)
Faculty of Medicine, Al-Azhar university Assiut, Egypt.
Asyut, Egypt