Clinical Research Directory

Inclusion Criteria: * 1\. Male or female aged 45 to 85 * 2\. Patients undergoing colonoscopy for colorectal cancer screening, positive fecal immunochemical test (FIT) results, gastrointestinal symptoms, or follow-up examination after colorectal polyp treatment * 3\. Capable of providing informed consent and agreeing to participate * 4\. Able and willing to follow all research processes Exclusion Criteria: * 1\. Participated in other clinical trials, signed informed consent form, and in the follow-up period of other clinical trials; * 2\. Participated in clinical trials of drugs and is in the discontinuation period of experimental or control drugs; * 3\. Have had drug or alcohol abuse or psychological disorders in the past five years. * 4\. Pregnant or lactating patients; * 5\. Known to have polyposis syndrome; * 6\. Patients with gastrointestinal bleeding; * 7\. Previous history of inflammatory bowel disease, colorectal cancer, or colorectal surgery; * 8.Patients with contraindications to tissue biopsy; * 9\. History of allergies to the ingredients in intestinal cleansers; * 10\. Individuals with conditions such as intestinal obstruction or perforation, toxic megacolon, heart failure (grade III or IV), severe cardiovascular disease, severe liver failure, or renal insufficiency, among others. * 11\. Researchers believe that patients are not suitable to participate in the trial.