Clinical Research Directory

Inclusion Criteria: 1. Age 18 or above 2. Previously diagnosed with Congestive Heart Failure (HFpEF or HFrEF) 3. Fluid overload due to worsening HF requiring parenteral diuretic treatment as assessed by at least 2 of the following: 1. BNP \> 200 2. JVP \> 10cmH20 3. Presence of S3 4. LE Edema 5. Weight gain of \> 5lbs in the past 5 days 4. Failed oral uptitration of loop diuretic over the prior 5 days or presented with symptoms too advance to justify additional oral uptitration attempts to resolve congestion symptoms. 5. Expected to require a minimum of three days of parenteral diuretic treatment 6. Written informed consent 7. Able and willing to operate Lasix ONYU and comply with study requirements or has a caregiver who can assume these roles. Exclusion Criteria: 1. Age above 80 years 2. Unable or unwilling to provide informed consent. 3. Any medical condition or circumstances that would require further clinical investigation or hospitalization 4. Presence or history of electrolyte abnormalities that may be exacerbated by parenteral loop diuretic treatment 5. Home or current living environment not suitable for outpatient management and diuresis 6. Pregnant or breastfeeding 7. Unable to comply with clinic-required follow up procedure 8. Baseline chronic renal disease with CKD Stage V 9. Any surgical or medical condition which, in the opinion of the investigator, may pose an undue risk to the subject, interfere with participation in the study or which may affect the integrity of the data