Clinical Research Directory

Inclusion Criteria: * 40 to ≤ 80 years old * BMI ≥ 18.0 kg/(m\*m) * COPD diagnosis≥1 year * Post-BD FEV1 ≥ 30% and \< 80%, FEV1/FVC \<0.70 at screening * Triple (LABA+LAMA+ICS) or dual inhaled (LABA+LAMA or LABA+ICS) COPD therapy ≥3 months prior to V1 * 2 moderate or ≥1 severe COPD exacerbations in the prior year * CAT ≥10 at screening * Former or current smokers ≥10 pack-years Exclusion Criteria: * Clinically important pulmonary disease other than COPD, as judged by the Investigator (including current or historic asthma diagnosis). * Any disorder, including, but not limited to, cardiovascular, gastrointestinal, hepatic, renal, neurological, musculoskeletal, infectious, endocrine, metabolic, hematological, psychiatric, or major physical impairment that is not stable. * Treatment with oxygen of more than 15 hours per day. * Pregnant or breastfeeding. * The chest/lungs with pathology that precludes the patient's ability to complete the study.