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RECRUITING
NCT06980376
NA

Milk Free From A1-Type β-Casein on Inflammation, Gastrointestinal Tolerance, and Pregnancy Outcomes

Sponsor: a2 Milk Company Ltd.

View on ClinicalTrials.gov

Summary

The aim of the study is to compare the effects of conventional Ultra High Temperature (UHT) milk containing both A1 and A2 type β-caseins (CON) with a2 UHT Milk containing A2 type β-casein only (A1PF) on inflammation, tolerance, and GI symptoms in pregnant women as well as infants' birth outcomes from 12 weeks' gestation up to 40 days post-birth.

Official title: Effects of Milk Free From A1-Type β-Casein on Inflammation, Gastrointestinal Tolerance, and Pregnancy Outcomes: A Multi-Centre, Randomised, Open-Label, Prospective Study

Key Details

Gender

FEMALE

Age Range

20 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2025-08-25

Completion Date

2026-09

Last Updated

2026-02-06

Healthy Volunteers

Yes

Interventions

OTHER

a2 UHT milk

Pregnant women in this arm will drink a2 UHT Milk twice a day, 200ml each time, until study completion. Their infants will be fed with the mother's breastmilk exclusively.

OTHER

Conventional UHT Milk

Pregnant women in this arm will drink conventional UHT Milk twice a day, 200ml each time, until study completion. Their infants will be fed with the mother's breastmilk exclusively.

Locations (6)

Foshan Maternity & Child Healthcare Hospital

Foshan, Guangdong, China

Panyu Maternal and Child Care Service Centre of Guangzhou

Guangzhou, Guangdong, China

Wuxi Maternal and Child Health Hospital

Wuxi, Jiangsu, China

Affiliated hospital of Jiangnan University

Wuxi, Jiangsu, China

Xuzhou Maternal and Child Health Hospital

Xuzhou, Jiangsu, China

First People's Hospital of Chengdu

Chengdu, Sichuan, China