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Milk Free From A1-Type β-Casein on Inflammation, Gastrointestinal Tolerance, and Pregnancy Outcomes
Sponsor: a2 Milk Company Ltd.
Summary
The aim of the study is to compare the effects of conventional Ultra High Temperature (UHT) milk containing both A1 and A2 type β-caseins (CON) with a2 UHT Milk containing A2 type β-casein only (A1PF) on inflammation, tolerance, and GI symptoms in pregnant women as well as infants' birth outcomes from 12 weeks' gestation up to 40 days post-birth.
Official title: Effects of Milk Free From A1-Type β-Casein on Inflammation, Gastrointestinal Tolerance, and Pregnancy Outcomes: A Multi-Centre, Randomised, Open-Label, Prospective Study
Key Details
Gender
FEMALE
Age Range
20 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-08-25
Completion Date
2026-09
Last Updated
2026-02-06
Healthy Volunteers
Yes
Conditions
Interventions
a2 UHT milk
Pregnant women in this arm will drink a2 UHT Milk twice a day, 200ml each time, until study completion. Their infants will be fed with the mother's breastmilk exclusively.
Conventional UHT Milk
Pregnant women in this arm will drink conventional UHT Milk twice a day, 200ml each time, until study completion. Their infants will be fed with the mother's breastmilk exclusively.
Locations (6)
Foshan Maternity & Child Healthcare Hospital
Foshan, Guangdong, China
Panyu Maternal and Child Care Service Centre of Guangzhou
Guangzhou, Guangdong, China
Wuxi Maternal and Child Health Hospital
Wuxi, Jiangsu, China
Affiliated hospital of Jiangnan University
Wuxi, Jiangsu, China
Xuzhou Maternal and Child Health Hospital
Xuzhou, Jiangsu, China
First People's Hospital of Chengdu
Chengdu, Sichuan, China