Clinical Research Directory
Browse clinical research sites, groups, and studies.
PVI Predictors in Laparoscopic Hysterectomy
Sponsor: Wonkwang University Hospital
Summary
This observational study investigates the predictors of Pleth Variability Index (PVI) changes in euvolemic patients undergoing laparoscopic-assisted vaginal hysterectomy (LAVH). The primary objective is to quantify changes in PVI (ΔPVI) across six intraoperative time points associated with positional shifts. Secondary objectives include identifying key predictors of significant PVI change (ΔPVI ≥ 5%), such as passive leg raising, Trendelenburg position, body mass index (BMI), and intraabdominal pressure. Additional variables including perfusion index, mean arterial pressure, bispectral index, skin temperature, age, and anesthetic agent will be evaluated as potential modulators. Findings aim to support individualized fluid management strategies in LAVH.
Official title: Predictors of Pleth Variability Index During Laparoscopically Assisted Vaginal Hysterectomy
Key Details
Gender
FEMALE
Age Range
19 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2026-07-01
Completion Date
2026-08-20
Last Updated
2026-07-06
Healthy Volunteers
Not specified
Conditions
Interventions
Masimo Radical-7 Pulse Oximeter
"PVI is continuously monitored using the Masimo Radical-7 pulse oximetry device to evaluate respiratory variation in the plethysmographic waveform amplitude during laparoscopic-assisted vaginal hysterectomy (LAVH). No fluid intervention is applied; device use is for observational measurement of fluid responsiveness."
Locations (1)
Wonkwang University School of Medicine Hospital
Iksan, Jeollabuk-do, South Korea