Clinical Research Directory

Inclusion Criteria: 1. Patients received at least 1 lines of systemic therapy 2. Previously received anti- CD20 treatment 3. Subjects must have at least one bi-dimensionally measurable lesion (nodal site Ldi \> 1.5 cm or extranodal site Ldi \> 1.0cm) 4. Patients must have an acceptable organ function Exclusion Criteria: 1. Previously treated with PI3K inhibitors 2. Unresolved toxicity of CTCAE grade \> 1 from prior anti-lymphoma therapy 3. Chemotherapy or other antitumor therapy within 14 days before starting cycle one 4. Significant concurrent medical disease or condition which according to the investigators' judgement 5. Active hepatitis B, C or HIV infection 6. Infection requiring treatment 2 weeks prior to the first dosing