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RECRUITING
NCT06984146
PHASE2

Nivo40-AVD for Advanced Classic Hodgkin Lymphoma

Sponsor: National Medical Research Radiological Centre of the Ministry of Health of Russia

View on ClinicalTrials.gov

Summary

The aim of the current trial is to evaluate the efficacy and safety of flat-dose nivolumab (40 mg) in combination with AVD in the management of patients with newly diagnosed advanced classic Hodgkin Lymphoma

Official title: Flat-dose Nivolumab (40 mg) in Combination With Doxorubicin, Vinblastine, and Dacarbazine (AVD) for Newly Diagnosed Advanced Classic Hodgkin Lymphoma

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

54

Start Date

2025-04-15

Completion Date

2029-01

Last Updated

2025-11-26

Healthy Volunteers

No

Interventions

DRUG

Nivolumab

40 mg day 1 and 15

DRUG

Doxorubicin

25 mg/m2 day 1 and 15

DRUG

Vinblastine

6 mg/m2 (not exceeding 10 mg) day 1 and 15

DRUG

Dacarbazine

375 mg/m2 day 1 and 15

Locations (1)

P. Hertsen Moscow Oncology Research Institute (MORI) for administrative and economic work - the branch of the FSBI "National Medical Research Radiological Centre" (NMRRC) of the Ministry of Health of the Russian Federation

Moscow, Russia