Clinical Research Directory

Inclusion Criteria: 1. ≥18 years of age, diagnosed with nonvalvular atrial fibrillation; 2. Meet the indications for receiving WATCHMAN FLX left atrial appendicular closure and transcatheter atrial fibrillation ablation; 3. Preoperative imaging evaluation showed that the anatomical structure of the left atrial appendage was suitable for implantation with the WATCHMAN FLX device; 4. The patient agrees to participate in the study and signs the informed consent. Exclusion Criteria: 1. valvular heart disease or other structural heart disease that causes atrial fibrillation; 2. left auricular thrombus or acute thrombotic event was found before surgery; 3. Patients with severe bleeding tendency or recent major bleeding events (such as massive gastrointestinal bleeding, cerebral hemorrhage, etc.); 4. Patients who are unable to complete postoperative follow-up (such as life expectancy of less than 1 year or poor compliance); 5. Other serious diseases (such as liver and kidney failure, active infection, etc.) were found in preoperative examination; 6. Pregnant or lactating women.