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NOT YET RECRUITING
NCT06986291
NA

Radiation-induced Toxicity of the Heart

Sponsor: Technische Universität Dresden

View on ClinicalTrials.gov

Summary

Late side effects in radio(chemo)therapy \[R(CH)T\] pose a critical limitation to patients' overall survival and quality of life. Even though toxicities of the heart are highly relevant for patients with cancer in the thoracic region, risk stratification models for these toxicities are lacking. In this study, liquid, functional and imaging biomarkers are being investigated for their use in prediction of cardiac toxicity following R(CH)T for patients with thoracic malignancies.

Official title: Quantitative Assessment of Radiation-induced Toxicity of the Heart

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

325

Start Date

2025-08

Completion Date

2039-12

Last Updated

2025-05-29

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Imaging and biomarkers

MR imaging of the heart, ECG and TTE measurements, blood sample

Locations (1)

University of Technology, University Hospital Carl Gustav Carus, Department of Radiation Therapy and Radiation Oncology

Dresden, Germany, Germany