Clinical Research Directory

Inclusion Criteria: 1. Participants suffering from mild to moderate symptoms (baseline Total nasal symptoms score ≤ 9). 2. Subjects age range from 20 to 40 years old. 3. Patients of both sexes. 4. proven positive allergy test (skin prick test or multiple allergen simultaneous test) to any of the common perennial allergens such as dust mites, molds, insects, and animal dander within the last 12 months Exclusion Criteria: * Pregnant or breastfeeding women. * Patients with a definite deviated nasal septum, or history of operation within the last 6 months. * Hypertension, diabetes mellitus, malignancy, active pulmonary tuberculosis, active respiratory disease like asthma, or other systemic diseases. * Long-term use of corticosteroids or immunosuppressive agents. * Participation in another clinical study within 30 days. * Hyperthyroidism * Patients who had used antihistamines within 1 week, topical corticosteroids within 2 weeks, systemic corticosteroids within 4 weeks, anticholinergic drugs within 3 days, antileukotriene drugs within 1 week, decongestants within 3 days, tricyclic antidepressants or phenothiazines within 2 weeks, nonsteroidal analgesics within 2 weeks, and other drugs that the researchers believed were inappropriate. * Patients with Tattoos, moles and dark skin