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Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)
Sponsor: Assiut University
Summary
Postoperative respiratory failure (PORF) remains a critical driver of morbidity, mortality, and incremental care costs in surgical populations. Traditional escalation often involves invasive mechanical ventilation, which is associated with ventilator-associated pneumonia (VAP), prolonged intensive care unit (ICU) stays, and increased resource burden.
Official title: A Prospective, Randomized Controlled Trial Comparing Noninvasive Ventilation (NIV) Versus High-Velocity Nasal Cannula (HVNC) in the Management of Acute Post-Operative Respiratory Failure
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2025-07-01
Completion Date
2026-12-01
Last Updated
2025-05-23
Healthy Volunteers
No
Conditions
Interventions
BIPAP
The second arm (NIV group) will be managed by BIPAP device for post-operative respiratory failure
Vapotherm
The first arm (HVNC group) will be managed by Vapotherm device for post-operative respiratory failure
Locations (1)
Assuit Univeristy
Asyut, Assuit, Egypt