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NOT YET RECRUITING
NCT06988111
NA

Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)

Sponsor: Assiut University

View on ClinicalTrials.gov

Summary

Postoperative respiratory failure (PORF) remains a critical driver of morbidity, mortality, and incremental care costs in surgical populations. Traditional escalation often involves invasive mechanical ventilation, which is associated with ventilator-associated pneumonia (VAP), prolonged intensive care unit (ICU) stays, and increased resource burden.

Official title: A Prospective, Randomized Controlled Trial Comparing Noninvasive Ventilation (NIV) Versus High-Velocity Nasal Cannula (HVNC) in the Management of Acute Post-Operative Respiratory Failure

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

180

Start Date

2025-07-01

Completion Date

2026-12-01

Last Updated

2025-05-23

Healthy Volunteers

No

Interventions

DEVICE

BIPAP

The second arm (NIV group) will be managed by BIPAP device for post-operative respiratory failure

DEVICE

Vapotherm

The first arm (HVNC group) will be managed by Vapotherm device for post-operative respiratory failure

Locations (1)

Assuit Univeristy

Asyut, Assuit, Egypt