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Lipid Emulsion for Reversal of Spinal Anesthesia in Ambulatory Surgery
Sponsor: Zagazig University
Summary
Ambulatory surgery places high demands on anesthetic technique. rapid onset and offset of anesthesia, rapid recovery of protective reflexes, mobility and micturition, are required. Since the inception of ambulatory surgery, the favored anesthetic technique has been general anesthesia with short-acting drugs. Concerns about the time to perform spinal anesthesia and the risks of prolonged motor block and urinary retention have limited its use. Alpha-blockers, lavage fluids for epidural space, insulin, and intravenous lipid emulsions, are still being discussed to shorten and reverse adverse effect of different LAs used for spinal anaesthesia, hence we will evaluate the effectiveness of intravenous lipid emulsion for reversing the neural blockade of spinal anaesthesia in patients undergoing ambulatory surgery.
Official title: Lipid Emulsion for Reversal of Spinal Anesthesia in Ambulatory Surgery: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
21 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
42
Start Date
2025-06-01
Completion Date
2026-01-01
Last Updated
2025-05-25
Healthy Volunteers
No
Interventions
Intravenous Lipid Emulsion 20%
patients will receive 1.5 ml/kg bolus of intravenous lipid emulsion 20 % followed by 0.25 ml/kg/hr infusion over 30 minutes at the end of surgery
Control (placebo) group
patients will receive equal volume of normal saline at the end of surgery
Locations (1)
Zagazig University Hospitals
Zagazig, Al Sharqia, Egypt