Clinical Research Directory
Browse clinical research sites, groups, and studies.
Clinical Outcomes and Ejaculatory Function in BPO Patients Treated With Silodosin
Sponsor: Marmara University
Summary
This observational study aims to evaluate the relationship between silodosin-induced anejaculation and clinical outcomes in male patients with benign prostatic obstruction (BPO). Silodosin is a commonly used alpha-blocker for lower urinary tract symptoms (LUTS). However, it may cause ejaculatory dysfunction, particularly anejaculation. In this study, patients receiving silodosin for the first time will be grouped based on whether they experience anejaculation or not. Treatment response will be assessed using urinary flow rate, post-void residual urine, and International Prostate Symptom Score (IPSS). Sexual function will be evaluated using the International Index of Erectile Function-5 (IIEF-5) before and after treatment. The study aims to explore whether the presence of anejaculation is associated with improved symptom relief or differences in sexual health.
Official title: Does Anejaculation Reflect Better Clinical Outcomes in BPO Patients Receiving Silodosin?
Key Details
Gender
MALE
Age Range
40 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-06-15
Completion Date
2026-06-12
Last Updated
2025-06-05
Healthy Volunteers
No