Clinical Research Directory

Inclusion Criteria: Patients with Stargardt disease * Age: 18 - 70 ; * Juvenile form of Stargardt's disease manifested by decreased visual acuity; * Visual acuity greater than or equal to 20/400 in binocular vision; * MMSE score without visual item ≥ 20/25 ; * Eyes whose palpebral opening and ocular surface and its appendages allow the wearing of a scleral lens; * Sufficient knowledge of the French language. * Ability to give express, free and informed consent in person, after having received adequate information; * Ability to comply with protocol requirements; * Person covered by Health Insurance. Healthy volunteers: * Age: 18 - 70 years; * Age- and sex-matched healthy volunteers to subjects with Stargardt's disease (± 5 years); * MMSE score with visual items ≥ 25/30 ; * Eyes with palpebral opening and ocular surface and appendages suitable for scleral lens wear; * Visual acuity of at least 10/10 in binocular vision; * Sufficient knowledge of the French language; * Ability to give personal, express, written, free and informed consent after receiving adequate information ; * Ability to comply with protocol requirements; * Person covered by Health Insurance. Exclusion Criteria: For all participantsPersons referred to in articles L1121-5 to L1121-8 of the CSP (corresponding to all protected persons : pregnant women, parturients, nursing mothers, persons deprived of liberty by judicial or administrative decision, minors, and persons subject to a legal protection measure: guardianship or curatorship); * Participants with neurodegenerative diseases or any other disease that could interfere with the planned evaluations during this study; * Participants with ophthalmological diseases other than Stargardt's disease; * Participants with a history of cleft palate, corneal infection, irregular cornea (such as keratoconus) and severe dry eye syndrome as determined by the ophthalmologist; * Participants allergic or sensitive to methyl acrylic poly methacrylate (PMMA) or to any of the components of the Re-See lens; * Participants allergic to tropicamide, atropine or its derivatives * Participants at risk of angle-closure glaucoma; * Participants allergic to sodium fluorescein; * Suspicion of transmissible spongiform encephalopathy; * Medications that may cause motor, visual or cognitive disorders (neuroleptics, etc.) or that may interfere with study evaluations; * Participation in another clinical trial that could interfere with the present study; * Inability to follow instructions or read. ☞Wearing glasses or contact lenses is not a non inclusion criterion.