Clinical Research Directory
Browse clinical research sites, groups, and studies.
Implementation of a Multiple Intervention to Promote Healthy Lifestyles in Patients With Depression
Sponsor: IRCCS Centro San Giovanni di Dio Fatebenefratelli
Summary
This clinical trial aims to investigate whether an integrative approach combining education on the Mediterranean diet and physical activity (PA) can significantly reduce depressive symptomatology in individuals with major depressive disorder. The study will evaluate changes in depressive symptoms and assess biological modulations, including alterations in the gut microbiota and inflammatory markers, resulting from the PA intervention. Participants will be randomized into two arms: the active control group will attend a series of lessons focused on the Mediterranean diet, while the experimental group will participate in the same dietary lessons combined with a structured PA program of 12 weeks.
Official title: Implementazione di un Intervento Multiplo Per Promuovere Stili di Vita Sani in Pazienti Con Depressione: Uno Studio Clinico Controllato e Randomizzato
Key Details
Gender
All
Age Range
55 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2025-07
Completion Date
2026-02
Last Updated
2025-05-25
Healthy Volunteers
No
Conditions
Interventions
Mediterranean diet lessons program
Participants will attend five one-hour lessons delivered by qualified professionals to learn about foods that have a positive impact on cognitive function and how to incorporate them into their dietary regimen.
Physical activity
Participants will undergo a 12-week physical exercise program guided by specified personal trainers.
Locations (1)
IRCCS Centro San Giovanni fi Dio Fatebenefratelli
Brescia, Italy