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Comparison of Needling and Microneedling Plus Phototherapy in Localized Vitiligo Patients
Sponsor: Khyber Teaching Hospital
Summary
This randomized controlled trial aims to compare the efficacy of needling versus microneedling, both followed by narrowband UVB therapy, in achieving repigmentation in patients with localized stable non-segmental vitiligo.
Official title: Puncture to Repigment: A Comparative Analysis Of Needling vs. Microneedling Along With NBUVB in Treatment of Non-Segmental Vitiligo
Key Details
Gender
All
Age Range
15 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2025-03-01
Completion Date
2025-08-31
Last Updated
2025-09-02
Healthy Volunteers
No
Conditions
Interventions
Needling + NBUVB
Participants in this arm will undergo needling using a sterile 30G (4mm) needle to manually puncture and implant melanocytes from perilesional pigmented skin into depigmented lesions. The procedure will be performed once every four weeks for a total of six sessions.
Microneedling + NBUVB
Participants in this arm will undergo microneedling using a Dermapen device with 1.5 mm needles to create controlled micro-injuries in depigmented skin to enhance melanocyte migration and repigmentation. This procedure will be performed once every four weeks for six sessions.
Locations (1)
Khyber Teaching Hospital
Peshawar, Khyber Pakhtunkhwa, Pakistan