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Risk Assessment of Mild Traumatic Brain Injury in Military Training
Sponsor: Charles University, Czech Republic
Summary
The SNIPER-TBI study aims to identify and quantify the risk of mild traumatic brain injury (mTBI) in soldiers of the Czech Armed Forces during specific high-risk training activities, including parachute jumps, high-caliber firearms shooting, artillery blasts, and Close Quarters Battle (CQB) exercises. The study will utilize both diagnostic biomarker analysis and experimental biomechanical measurements to assess the physiological impact of these activities on brain health. The ultimate goal is to reduce mTBI incidence, improve operational readiness, and extend the active service duration of soldiers through targeted preventive measures.
Official title: Identification and Risk Assessment of Mild Traumatic Brain Injury (mTBI) in Czech Armed Forces Soldiers During Specific Training Activities
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2025-11-04
Completion Date
2026-09-30
Last Updated
2025-11-19
Healthy Volunteers
Yes
Conditions
Interventions
Quantification of mild trauma brain injury risk
Measure the incidence and severity of mTBI among soldiers engaged in high-risk training activities. (e.g. parachute jumps, high-caliber firearms shooting, artillery fire, explosions). Concentration of brain injury biomarkers (GFAP, UCH-L1) in blood samples collected within 24 hours post-exposure
Biomechanical Analysis of Head Impact Forces
Evaluate the mechanical forces experienced by soldiers during high-risk activities using wearable accelerometers and high-speed video analysis. Peak head acceleration (g-force) and pressure wave analysis during training activities.
Locations (1)
Military University Hospital Prague
Prague, Czech Republic, Czechia