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Impact of Ultraviolet Radiation and Environmental Factors on Human Ocular Biomechanics
Sponsor: Tianjin Eye Hospital
Summary
This observational study aims to explore whether ultraviolet (UV) radiation and other environmental factors are associated with ocular biomechanical properties in healthy volunteers aged 18-44 years without ocular diseases, ocular surgery history, or systemic diseases. The main questions it aims to answer are: Is there a significant correlation between UV radiation levels and corneal biomechanical parameters? Do environmental factors such as geographic region and seasonal variation affect corneal biomechanical behavior? Researchers will compare ocular biomechanical parameters among populations from different geographic regions with varying levels of UV radiation to determine whether there are statistically significant correlations or differences. Participants will: Undergo standardized ophthalmic examinations, including visual acuity, intraocular pressure, slit-lamp evaluation, axial length, and corneal topography; Receive corneal biomechanical assessments using the Corvis ST device; Provide basic demographic information and medical history; Have all data de-identified, with the study strictly following ethical approval and privacy protection protocols.
Official title: Association Between Ultraviolet Radiation, Environmental Factors, and Ocular Biomechanical Properties: A Multicenter Cross-Sectional Study
Key Details
Gender
All
Age Range
18 Years - 44 Years
Study Type
OBSERVATIONAL
Enrollment
3000
Start Date
2025-01-01
Completion Date
2025-10-01
Last Updated
2025-05-28
Healthy Volunteers
Yes
Conditions
Interventions
environment Exposure
No special intervention
Locations (1)
Tianjin Eye Hospital
China, Tianjin Municipality, China