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NCT06993077

Impact of Ultraviolet Radiation and Environmental Factors on Human Ocular Biomechanics

Sponsor: Tianjin Eye Hospital

View on ClinicalTrials.gov

Summary

This observational study aims to explore whether ultraviolet (UV) radiation and other environmental factors are associated with ocular biomechanical properties in healthy volunteers aged 18-44 years without ocular diseases, ocular surgery history, or systemic diseases. The main questions it aims to answer are: Is there a significant correlation between UV radiation levels and corneal biomechanical parameters? Do environmental factors such as geographic region and seasonal variation affect corneal biomechanical behavior? Researchers will compare ocular biomechanical parameters among populations from different geographic regions with varying levels of UV radiation to determine whether there are statistically significant correlations or differences. Participants will: Undergo standardized ophthalmic examinations, including visual acuity, intraocular pressure, slit-lamp evaluation, axial length, and corneal topography; Receive corneal biomechanical assessments using the Corvis ST device; Provide basic demographic information and medical history; Have all data de-identified, with the study strictly following ethical approval and privacy protection protocols.

Official title: Association Between Ultraviolet Radiation, Environmental Factors, and Ocular Biomechanical Properties: A Multicenter Cross-Sectional Study

Key Details

Gender

All

Age Range

18 Years - 44 Years

Study Type

OBSERVATIONAL

Enrollment

3000

Start Date

2025-01-01

Completion Date

2025-10-01

Last Updated

2025-05-28

Healthy Volunteers

Yes

Conditions

Interventions

OTHER

environment Exposure

No special intervention

Locations (1)

Tianjin Eye Hospital

China, Tianjin Municipality, China