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RECRUITING
NCT06993233
PHASE2

A Study With CIT-013 in HS Patients

Sponsor: Citryll BV

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if CIT-013 works to treat Hidradenitis Suppurativa in adults. It will also learn about the safety of CIT-013. The main questions it aims to answer are: Does CIT-013 lower the disease activity of HS patients? What medical problems do participants have when receiving CIT-013? Researchers will compare CIT-013 to a placebo (a look-alike substance that contains no drug) to see if CIT-013 works to treat the symptoms of HS. Participants will: Take receive 50 or 100 mg CIT-013 or placebo every other week for 12 weeks Visit the clinic once every 2 weeks for checkups and tests Keep monitor their symptoms during this period

Official title: A Phase 2a Double Blind, Randomized, Parallel Arm, Placebo-controlled Trial to Investigate the Effects of Two Dose Levels of CIT-013 on Disease Activity in Patients With Hidradenitis Suppurativa

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

96

Start Date

2025-10-31

Completion Date

2027-07

Last Updated

2026-03-25

Healthy Volunteers

No

Interventions

DRUG

CIT-013 high dose

subcutaneous injection

DRUG

CIT-013 medium dose

subcutaneous injection

DRUG

Placebo

subcutaneous injection

Locations (24)

CA-01

Barrie, Canada

CA-05

Calgary, Canada

CA-02

London, Canada

CA-04

Newmarket, Canada

CA-03

Winnipeg, Canada

DE-06

Bad Bentheim, Germany

DE-01

Bochum, Germany

DE-04

Dresden, Germany

DE-02

Frankfurt, Germany

DE-08

Kiel, Germany

DE-03

Oldenburg, Germany

Erasmus UMC

Rotterdam, Netherlands

PL-03

Katowice, Poland

PL-02

Lodz, Poland

PL-01

Rzeszów, Poland

PL-05

Wroclaw, Poland

ES-05

Barcelona, Spain

ES-04

Madrid, Spain

ES-02

Santiago de Compostela, Spain

ES-03

Seville, Spain

ES-01

Valencia, Spain

GB-02

Cardiff, United Kingdom

GB-05

Chester, United Kingdom

GB-04

London, United Kingdom