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RECRUITING
NCT06993636

Pharmacometrics Analysis of Rivaroxaban in Chinese Children Aged Over 2 Years

Sponsor: Children's Hospital of Fudan University

View on ClinicalTrials.gov

Summary

Based on an established Kawasaki disease cohort database, this prospective, single-center, single-arm, observational study will collect clinical data from children aged 2 years and older with giant coronary artery aneurysms after Kawasaki disease who received rivaroxaban treatment. Rivaroxaban plasma concentrations, anti-factor Xa activity levels, and genetic polymorphisms will be measured and analyzed to support the population pharmacokinetic/pharmacodynamic analysis

Official title: Population Pharmacokinetic/Pharmacodynamic Analysis of Rivaroxaban in Chinese Children Aged Over 2 Years With Giant Coronary Artery Aneurysm After Kawasaki Disease

Key Details

Gender

All

Age Range

2 Years - 18 Years

Study Type

OBSERVATIONAL

Enrollment

60

Start Date

2023-01-01

Completion Date

2026-12-31

Last Updated

2025-05-29

Healthy Volunteers

No

Locations (1)

Children's Hospital of Fudan University

Shanghai, Shanghai Municipality, China