Clinical Research Directory
Browse clinical research sites, groups, and studies.
Nitazoxanide in Patients With Ulcerative Colitis
Sponsor: Alexandria University
Summary
Ulcerative colitis (UC) is a chronic inflammatory bowel Disease (IBD) that primarily affects the rectum and colon. The severity and persistence of mucosal inflammation are associated with morbidity and mortality.
Official title: Clinical Study to Evaluate Safety and Efficacy of Nitazoxanide in Patients With Ulcerative Colitis.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2025-05-30
Completion Date
2026-12-20
Last Updated
2025-06-27
Healthy Volunteers
No
Conditions
Interventions
Mesalamine
Mesalamine or 5-amino salicylic acid (5-ASA), plays a crucial role in the treatment of ulcerative colitis (UC). It is the first-line therapy for mild to moderate cases of UC and is considered a cornerstone in its management.
Nitazoxanide
Nitazoxanide is an FDA-approved oral medication used to treat protozoal infections and is also effective against metronidazole-resistant Clostridium difficile colitis.
Locations (1)
Alexandria University
Alexandria, Egypt