Clinical Research Directory
Browse clinical research sites, groups, and studies.
Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy
Sponsor: Indiana University
Summary
The investigators are doing this study to discover if it is appropriate for people with Cystic Fibrosis (CF) on highly effective modulator therapy (HEMT) to stop using certain standard Sino nasal therapies such as high-volume nasal saline irrigations, topical nasal steroids, and topical nasal antibiotics. They are also going to study the fluid inside the nose to see if there are changes when stopping these therapies. Right now, they are not sure if it is suggested to stop these treatments when patients begin highly effective modulator therapy (HEMT)
Official title: Sinonasal Therapies and Histologic Correlations for Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2025-07-02
Completion Date
2026-07
Last Updated
2025-12-16
Healthy Volunteers
No
Interventions
STOP NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID
PATIENT WILL STOP USING NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID
CONTINUE NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID
PATIENT WILL CONTINUE USING NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID
Locations (1)
Indiana University Health
Indianapolis, Indiana, United States