Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT06997926
NA

Identification of the Mechanism of Non-histaminergic Itch Inducing Epigenetic Changes

Sponsor: Aalborg University

View on ClinicalTrials.gov

Summary

Itch is defined as an unpleasant sensation that evokes the desire to scratch. Chronic itch, defined as itch persisting for more that 6 weeks, is a key symptom in many diseases severely affects the quality of life of the affected patients and represents a substantial economic burden for the society. At present, there are no effective treatments for chronic itch diseases. Moreover, chronic itch patients express differences in their genes compared with people who do not suffer from itch. With this experiment, we wish to analyse differences in genes expression in healthy volunteers who have been exposed to artificial itch from small plant needles from the plant cowhage (mucuna pruriens) and compare them to controls who have not been exposed to itch.

Official title: Identification of the Mechanism of Non-histaminergic Itch Probing Epigenetic Changes Following Cowhage Application

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2025-05-15

Completion Date

2027-12-31

Last Updated

2025-06-04

Healthy Volunteers

Yes

Conditions

Interventions

PROCEDURE

blood sampling

Whole blood samples (5 mL per each time point, a total of 20 mL per subject) will be collected

Locations (1)

Aalborg University

Gistrup, Denmark