Clinical Research Directory

Inclusion Criteria: * Ages 50 years and above * Willing to undergo non-contrast MRI (e.g., no contraindications to MRI, such as cardiac pacemakers, non-compatible intracranial vascular clips or pregnancy). Exclusion Criteria: * History of autoimmune disease. * Cardiac events in the last six months. * Impaired function of the liver or kidneys (glomerular filtration rate \<60ml/min). * Current use of medications that influence sodium excretion (e.g. thiazide diuretics, SGLT2 inhibitors and spironolactone), and/or chemotherapy or antibiotic treatment. * Currently receiving phototherapy or taking systemic medications for atopic dermatitis including cyclosporine, methotrexate, or other broad immunosuppressive medications. (Patients on dupilumab will not be excluded if they have been on dupilumab for at least two months and still meet the criteria for severe disease.)