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Longitudinal Evaluation of Minimally Invasive Protocols for Dental Caries in Brazilian Schoolchildren
Sponsor: University of Nove de Julho
Summary
This multicenter longitudinal interventional study aims to evaluate minimally invasive protocols for the prevention and control of dental caries in Brazilian schoolchildren under routine public health conditions. In the first phase, 50,000 children aged 6 to 12 years from public schools in five Brazilian cities will undergo dental screening using ICDAS criteria and receive preventive and educational oral health measures. In the longitudinal treatment phase, 2,500 children diagnosed with active carious lesions will be managed according to ICDAS-based minimally invasive treatment protocols. Participants will be followed every three months for up to 24 months.
Official title: Longitudinal Evaluation of Minimally Invasive Protocols for the Prevention and Control of Dental Caries in Brazilian Schoolchildren: A Multicenter Study Protocol
Key Details
Gender
All
Age Range
6 Years - 12 Years
Study Type
INTERVENTIONAL
Enrollment
2500
Start Date
2026-02-28
Completion Date
2028-12
Last Updated
2026-05-15
Healthy Volunteers
Yes
Conditions
Interventions
Fluoride Varnish Application (Preventive Protocol)
Preventive application of Duraphat® fluoride varnish on permanent molars and incisors, with quarterly maintenance applications.
Fluoride Varnish for Active Enamel Lesions
Four weekly fluoride varnish applications for active white spot lesions, followed by quarterly maintenance applications.
Atraumatic Restorative Treatment (ART) Sealant
Placement of ART sealants with high-viscosity glass ionomer cement for ICDAS 3 lesions, followed by quarterly fluoride varnish applications.
Atraumatic Restorative Treatment (ART)
Atraumatic restorative treatment with high-viscosity glass ionomer cement for ICDAS 4-6 lesions, with optional use of PapacarieDUO® and quarterly fluoride varnish applications.
Locations (1)
Universidade Metropolitana de Santos - UNIMES
Santos, São Paulo, Brazil