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Diaphragmatic Function and Respiratory Drive in OSA and COPD
Sponsor: Nanjing Medical University
Summary
This cross-sectional observational study aims to assess the diaphragmatic morphofunction and respiratory drive characteristics among patients with obstructive sleep apnea (OSA), chronic obstructive pulmonary disease (COPD), overlap syndrome (OS), and healthy controls. Using ultrasound imaging and surface diaphragm electromyography (EMGdi), the study will explore group differences in diaphragmatic morphology, function, and respiratory drive indicators, and evaluate their clinical significance in disease differentiation and severity assessment.
Official title: Diaphragmatic Morphofunction and Respiratory Drive in OSA and COPD: Insights From Ultrasound and EMG-based Cross-Sectional Analysis
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2025-01-01
Completion Date
2025-08-31
Last Updated
2025-06-25
Healthy Volunteers
Yes
Conditions
Interventions
Diaphragmatic Ultrasound and EMG Assessment
Non-invasive assessment of diaphragmatic morphofunction and respiratory drive using ultrasound imaging and diaphragm electromyography (EMG). This evaluation will be performed once per participant without any therapeutic intervention.
Locations (1)
The First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China