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Penthrox in Otolaryngology
Sponsor: Sir Mortimer B. Davis - Jewish General Hospital
Summary
Our objective is to explore the use of methoxyflurane anesthesia as an adjunct analgesic to local anesthesia during in-office otolaryngology procedures in a prospective pilot study. The main outcome of this study will be patient satisfaction with the medication and analgesia. Secondary outcomes will include level of sedation and analgesia, patient-reported post-procedural pain levels, and any reported adverse events.
Official title: Inhaled Methoxyflurane for In-Office Procedures in Otolaryngology
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2025-06-01
Completion Date
2027-06-01
Last Updated
2025-06-04
Healthy Volunteers
No
Interventions
Methoxyflurane anesthesia
A single Penthrox (3mL) self-inhaler will be administered 5-minutes prior to the onset of the procedure, before local anesthesia. Patients will undergo the procedure, have post-procedural vital signs, and remain in clinic for observation for 30 minutes post-procedure per our usual post-procedure monitoring.