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ENROLLING BY INVITATION
NCT07004283

Fetal Magnetic Resonance Imaging: Z-score Reference Ranges for a Large Patient Population in Normal Neuroimaging Measurement

Sponsor: Guangzhou Women and Children's Medical Center

View on ClinicalTrials.gov

Summary

This study aims to establish the z score reference ranges of fetal head circumference and other measurement of fetal measurements including biparietal diameter, fronto-occipital diameter, length of the corpus callosum, lateral ventricle, transverse cerebellar diameter, height of the vermis, anteroposterior diameter of the vermis,height and width of normal fetuses from 18 to 40 weeks' gestation. Method-A cohort-based study was conducted on low-risk singleton pregnancies with healthy fetuses. The measurement was performed using simple 2-dimensional MRI on the typical fetal standard view. The reference ranges were constructed according to gestational age (GA), biparietal diameter (BPD), as independent variables based on the best-fit models, both mean and standard deviation (SD).

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

800

Start Date

2024-01-01

Completion Date

2030-12-30

Last Updated

2025-06-04

Healthy Volunteers

Yes

Locations (1)

Siemens Skyra 3.0T MRI

Guangzhou, Guangdong, China