Clinical Research Directory

Inclusion Criteria: 1. Age ≥21 years 2. Good general health (ASA I or II) 3. Willing and able to provide informed consent 4. Committed to follow-up appointments for 18 months 5. Root canal treated molars requiring restoration 6. Adequate remaining tooth structure: * Minimum 2mm ferrule height * Sufficient wall thickness (≥1.5mm) * At least 2 remaining walls 7. Opposing natural dentition or fixed prosthesis 8. Adequate periodontal health: * Probing depth ≤4mm * No bleeding on probing 9. Good oral hygiene with plaque score ≤20% 10. Sufficient mouth opening for clinical procedures 11. Normal occlusion and acceptable interocclusal space Exclusion Criteria: 1. Pregnant or lactating women 2. Severe bruxism or parafunctional habits 3. Active periodontal disease 4. Active caries or inadequate oral hygiene 5. Less than 2mm ferrule height after preparation 6. Apical pathology or inadequate root canal treatment 7. Tooth mobility grade II or III 8. Known allergy to materials used 9. Uncontrolled diabetes (HbA1c \>7.0%) 10. Radiation therapy in head and neck region 11. Temporomandibular joint disorders 12. History of poor compliance with dental appointments 13. Heavy smokers (\>10 cigarettes/day) 14. Chronic use of medications affecting salivary flow 15. Unable to understand study requirements 16. Evidence of pulpal or periapical pathology