Clinical Research Directory

Inclusion Criteria: 1. 20 - 70 years of age 2. Office SBP ≥150 mmHg and \<180 mmHg and DBP ≥90 mmHg 3. Individual is prescribed with one, two, or three antihypertensive medication classes 4. 24-hour ABPM average of SBP ≥135 and \<170 mmHg at Baseline Exclusion Criteria: 1. Prior renal denervation. 2. Individual lacks appropriate renal artery Anatomy 3. Has a renal artery stent 4. Individual has an estimated glomerular filtration rate (eGFR) of \<60 mL/min/1.73m2 5. Individual is taking SGLT2 inhibitors or GLP-1 agonists 6. Individual requires chronic oxygen support or mechanical ventilation 7. Primary pulmonary hypertension. 8. Secondary cause of hypertension 9. Pregnant, nursing or planning to become pregnant during the study. 10. Individual has a documented condition that would prohibit or interfere with ability to obtain an accurate blood pressure measurement 11. Individual is currently taking anti-mineralocorticoid drugs.