Clinical Research Directory

Inclusion Criteria: Participants must : * Be 18 years of age or older. * Be in good systemic health or have well-controlled systemic health. * Have a healthy or stable periodontium after conventional periodontal treatment. * Have good clinical gingival health or gingivitis on an intact or reduced periodontium, with or without a history of periodontitis * Maintain good oral hygiene. * Have a simplified plaque index and gingival bleeding index below 20% * Require two mucogingival surgeries involving bilateral epithelial-conjunctival graft harvesting (free gingival graft or de-epithelialised connective tissue graft). * The surgeries must treat single or multiple gingival recessions, or mucogingival defects around teeth or implants. Exclusion Criteria: * Smokers or users of other tobacco products * Pregnant participants * Participants who are uncooperative or have a psychological condition that makes free and informed consent or compliance with instructions impossible * Participants with a condition that impairs healing (e.g. poorly controlled diabetes, coagulation disorder, etc.) or the objective assessment of pain at the sampling site (e.g. autoimmune diseases, orofacial pain, etc.) * Participants regularly taking the following medications : non-steroidal anti-inflammatory drugs, bisphosphonates, sedatives, psychotropic drugs and corticosteroids. * During the study, those who develop a condition that interferes with healing, become smokers, start medication that acts on the central nervous system, do not adhere strictly to instructions or do not respect follow-ups. * Participants who have already received a palatal surgery in the past or whose palatal tissue thickness is less than 3 mm will not be excluded, to allow comparative analyses in sub-groups.