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RECRUITING
NCT07017478
EARLY_PHASE1

Mood Effects of Serotonin Agonists: Depression

Sponsor: University of Chicago

View on ClinicalTrials.gov

Summary

This study will examine the effect of a low dose of the 5HT2A agonist LSD (26 µg), compared to placebo, on acute and protracted mood states in individuals with depression. The investigators will assess the relationship between mood-related symptoms and EEG as a neurophysiological marker.

Key Details

Gender

All

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

48

Start Date

2025-06-09

Completion Date

2026-06-01

Last Updated

2025-07-03

Healthy Volunteers

Yes

Interventions

DRUG

LSD

The serotonin 2A receptor agonist LSD

DRUG

Placebo

Distilled water

Locations (1)

University of Chicago

Chicago, Illinois, United States