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RECRUITING
NCT07017478
EARLY_PHASE1
Mood Effects of Serotonin Agonists: Depression
Sponsor: University of Chicago
View on ClinicalTrials.gov
Summary
This study will examine the effect of a low dose of the 5HT2A agonist LSD (26 µg), compared to placebo, on acute and protracted mood states in individuals with depression. The investigators will assess the relationship between mood-related symptoms and EEG as a neurophysiological marker.
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
48
Start Date
2025-06-09
Completion Date
2026-06-01
Last Updated
2025-07-03
Healthy Volunteers
Yes
Conditions
Interventions
DRUG
LSD
The serotonin 2A receptor agonist LSD
DRUG
Placebo
Distilled water
Locations (1)
University of Chicago
Chicago, Illinois, United States