Clinical Research Directory
Browse clinical research sites, groups, and studies.
Cognitive Training and Exercise for Women With Breast Cancer and Cognitive Impairment
Sponsor: Universidad de Extremadura
Summary
Chemotherapy-related cognitive impairment is a prevalent and distressing condition among breast cancer survivors, adversely affecting memory, attention, and overall cognitive function, thereby diminishing quality of life. Emerging evidence suggests that multimodal interventions combining cognitive training and adapted physical exercise may mitigate these cognitive deficits and associated symptoms. This study aims to evaluate the efficacy of a 12-week structured intervention integrating cognitive training and supervised physical exercise in improving cognitive function, fatigue, sleep quality, psychological distress, and overall well-being in women with breast cancer. Furthermore, it seeks to determine the optimal timing for such interventions to maximize their effectiveness. A randomized controlled trial involving 220 participants will assess subjective and objective cognitive outcomes, brain activity, and physical performance. The findings from this research may contribute to the development of evidence-based rehabilitation strategies, enhancing cognitive health and quality of life in breast cancer patients.
Official title: Combined Intervention of Cognitive Training and Supervised Physical Exercise for Women With Breast Cancer and Chemotherapy-Related Cognitive Impairment: Study Protocol for a Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
220
Start Date
2025-09-01
Completion Date
2028-08-31
Last Updated
2025-06-12
Healthy Volunteers
No
Conditions
Interventions
Cognitive training
Combined Intervention of Cognitive Training and Supervised Physical Exercise
Psychoeducational therapy
According to standard clinical practice
Locations (1)
Facultad de Medicina y Ciencias de la Salud
Badajoz, Badajoz, Spain