Clinical Research Directory

Inclusion Criteria: * Adults 18-55 years of age at the time of signing the informed consent form with primary complaint of tinnitus; * Suffering from subjective tinnitus for at least 30 days; * Tinnitus whose level of severity is defined by Tinnitus Handicap Inventory (THI) values ≥12, * Tinnitus is constant in nature (defined as audible at least 75% of waking hours). Exclusion Criteria: * Very mild tinnitus (THI values \<12); * Tinnitus that is intermittent in nature; * Tinnitus described as non-auditory or pulsatile in nature; * Individuals with a history of vertigo or fluctuating hearing loss, such as that related to Menière's disease, chronic otitis, vestibular neuritis, neuroma, otosclerosis cholesteatoma, or temporomandibular joint disorder; * Individuals with a history of extreme sensitivity to cold or heat, including individuals with a past history of frostbite or Raynaud's Syndrome. * Those who are currently receiving medical, pharmacologic, or therapeutic intervention for tinnitus or other otologic conditions, including sound therapy, cognitive behavioral therapy (CBT), Tinnitus Retraining Therapy (TRT), steroid injections, or other treatments; * Those who present with a mental health score indicating significant psychological component, per standard of care, based on PHQ-4 score of moderate to severe anxiety/depression. * Children (under 18 years), incarcerated individuals, adults unable to consent, and psychologically vulnerable participants.