Clinical Research Directory

Inclusion Criteria: * Men and women aged ≥18; * Those living in plains and preparing to move to the plateau for a short-term or medium-term period; * Can understand the research requirements and be willing to sign a written informed consent form (ICF). Exclusion Criteria: * Past history of contraindicated plateau travel: such as advanced COPD (FEV₁\<30% of the expected value or requires continuous oxygen therapy), advanced cystic fibrosis (FEV₁\<30% of the expected value or requires continuous oxygen therapy), advanced restricted pulmonary disease (FEV₁\<50% of the expected value or requires continuous oxygen therapy), decompensated heart failure, high-risk pregnancy, myocardial infarction or stroke occurred within 90 days, poorly controlled epilepsy, pulmonary hypertension (PASP\>90mmHg), sickle cell anemia, unstable angina pectoris, high-risk cerebrovascular abnormalities that have not been treated, etc.