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RECRUITING
NCT07019012
PHASE4

Cofrogliptin Once Every 2 Weeks as Add-on Therapy to Metformin and Dapagliflozin Versus Daily Linagliptin in Patients With Type 2 Diabetes.

Sponsor: Huazhong University of Science and Technology

View on ClinicalTrials.gov

Summary

This study is designed to evaluate the change in glycated hemoglobin (HbA1c) levels from baseline to 24 weeks after the combination therapy of cofrogliptin, metformin and SGLT2i (dapagliflozin) in type 2 diabetes mellitus (T2DM) patients with poor control of glucose level by metformin and SGLT2i combination therapy.

Official title: Cofrogliptin Once Every 2 Weeks as Add-on Therapy to Metformin and Dapagliflozin Versus Daily Linagliptin in Patients With Type 2 Diabetes: A Multicenter, Randomized, Open-Label, Active-Controlled, Non-inferiority Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

170

Start Date

2025-07-30

Completion Date

2026-12-30

Last Updated

2025-06-13

Healthy Volunteers

No

Conditions

Interventions

DRUG

SGLT2i+Metformin+Cofrogliptin

The combination of SGLT2i+Metformin+Cofrogliptin

DRUG

SGLT2i+Metformin+Linagliptin

The combination of SGLT2i+Metformin+Linagliptin

Locations (2)

Wuhan University People's Hospital

Wuhan, Hubei, China

Wuhan University People's Hospital

Wuhan, Hubei, China