Clinical Research Directory

Inclusion Criteria: 1. The patient is aged 18-80 years old; 2. Diagnosed as type 1 or type 2 diabetes according to the World Health Organization standard, blood sugar has been controlled before enrollment, and the level of Glycated hemoglobin HbA1c is less than 10%; 3. Abnormal renal function defined as: * Serum creatinine \>106 μmol/L (men) or \>97 μmol/L (women) * AND eGFR \<90 mL/min/1.73m² (CKD-EPI) ； 4. The patient has diabetes wounds with poor healing or prolonged healing need standard wound treatment; 5. After preparing the wound bed, the condition for using platelet plasma to close the wound is met\*; 6. Voluntarily sign an informed consent form; Exclusion Criteria: 1. Blood glucose is out of control or not yet effectively controlled，; 2. Severe diseases such as acute myocardial infarction, heart failure, hepatitis, shock, and respiratory failure have not been corrected yet; 3. Active bleeding inside the wound, and routine basic treatment plans cannot be implemented； 4. Uncontrolled systemic or disseminated infections; 5. Patients with advanced malignant tumors; 6. Pregnant or lactating women； 7. The patient is unable to cooperate or has mental disorders; 8. According to the judgment of the researchers, the patient has a clear and irremovable cause that affects wound healing, which is not suitable for this study or cannot comply with the requirements of this study.