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Mild TBI in the Emergency Department
Sponsor: Mario Negri Institute for Pharmacological Research
Summary
Mild TBI is one of the main causes of admission to the Emergency Department (ED). Brain computed tomography (CT) is one of the most widely used diagnostic tools to assess the presence of intracranial lesions. However, in Western countries, 85-95% of CT scans performed in the ED for mild TBI are negative. It is therefore conceivable that a significant number of CTs could be avoided by a more careful use of this exam. On the other hand, excessive use of CT exposes patients to unnecessary radiation, increases healthcare costs and slows down the management of patients in the ED. This study aims to analyze the variability in the use of CT in mild TBI in Italian EDs, validate the scores designed to help the physician decide when to use it and develop a model that predicts the medium-term outcome of patients with mild head trauma.
Official title: The Use of Brain Computed Tomography in the Management of the Patient With Mild TBI in the Emergency Department
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2500
Start Date
2026-01-21
Completion Date
2027-08-31
Last Updated
2026-10-07
Healthy Volunteers
No
Conditions
Locations (59)
Ospedale Civile San Giacomo
Novi Ligure, AL, Italy
Ospedale Mellino Mellini
Chiari, BS, Italy
Ospedale S. Maria Annunziata
Bagno a Ripoli, FI, Italy
Ospedale Fornaroli di Magenta
Magenta, MI, Italy
Ospedale di Foligno
Foligno, PG, Italy
Ospedale San Matteo degli Infermi
Spoleto, PG, Italy
Ospedale Santa Maria dei Battuti
San Vito al Tagliamento, PN, Italy
Ospedali Riuniti di Anzio e Nettuno
Anzio, RM, Italy
Ospedale Civico
Chivasso, TO, Italy
Presidio Ospedaliero S'Antonio Abate
Tolmezzo, UD, Italy
Ospedale Città del Piave
San Donà di Piave, VE, Italy
AOU Ospedale Civile SS.Antonio e Biagio
Alessandria, Italy
San Donato
Arezzo, Italy
Ospedale San Bassiano
Bassano del Grappa, Italy
Ospedale Bentivoglio
Bentivoglio, Italy
Ospedale Papa Giovanni XXIII
Bergamo, Italy
Ospedale degli Infermi
Biella, Italy
Ospedale Maggiore "CA Pizzardi"
Bologna, Italy
Policlinico Sant'Orsola - Malpighi
Bologna, Italy
Spedali Civili
Brescia, Italy
Ospedale Unico della Versilia
Camaiore, Italy
Ospedale Cardarelli
Campobasso, Italy
AOU Policlinico San Marco - PO San Marco
Catania, Italy
AOU Policlinico San Marco-PO Gaspare Rodolico
Catania, Italy
Ospedale San Martino
Genova, Italy
Ospedale Misericordia
Grosseto, Italy
Ospedale Alessandro Manzoni
Lecco, Italy
Spedali Riuniti
Livorno, Italy
Ospedale Maggiore
Lodi, Italy
Ospedale Carlo Poma
Mantua, Italy
ASST Ca' Granda Niguarda
Milan, Italy
ASST Fatebenefratelli Sacco, P.O. Luigi Sacco
Milan, Italy
IRCCS Ospedale San Raffaele
Milan, Italy
Ospedale Fatebenefratelli e Oftalmico
Milan, Italy
Policlinico di Milano Ospedale Maggiore
Milan, Italy
Azienda Ospedaliero-Universitaria Maggiore della Carità
Novara, Italy
AOU San Luigi Gonzaga
Orbassano, Italy
AOU Padova
Padova, Italy
Ospedale E. Agnelli Pinerolo
Pinerolo, Italy
AOU Pisana
Pisa, Italy
Ospedale Santa Maria degli Angeli
Pordenone, Italy
Ospedale Santa Maria delle Grazie
Pozzuoli, Italy
Ospedale Santa Maria delle Croci
Ravenna, Italy
Ospedale Infermi
Rimini, Italy
Ospedale degli Infermi
Rivoli, Italy
Azienda Ospedaliera San Camillo Forlanini
Roma, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, Italy
Istituto Clinico Humanitas
Rozzano, Italy
Ospedale Madonna del Soccorso
San Benedetto del Tronto, Italy
Ospedale SS. Annunziata
Sassari, Italy
Humanitas Gradenigo
Torino, Italy
Ospedale San Giovanni Bosco
Torino, Italy
Ospedale Santa Chiara
Trento, Italy
Ospedale Ca' Foncello
Treviso, Italy
Ospedale di Circolo
Varese, Italy
P.O. Sant'Andrea
Vercelli, Italy
Ospedale Michele e Pietro Ferrero
Verduno, Italy
Ospedale Civile
Voghera, Italy
Ente Ospedaliero Cantonale
Lugano, Switzerland