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RECRUITING
NCT07021118

Mild TBI in the Emergency Department

Sponsor: Mario Negri Institute for Pharmacological Research

View on ClinicalTrials.gov

Summary

Mild TBI is one of the main causes of admission to the Emergency Department (ED). Brain computed tomography (CT) is one of the most widely used diagnostic tools to assess the presence of intracranial lesions. However, in Western countries, 85-95% of CT scans performed in the ED for mild TBI are negative. It is therefore conceivable that a significant number of CTs could be avoided by a more careful use of this exam. On the other hand, excessive use of CT exposes patients to unnecessary radiation, increases healthcare costs and slows down the management of patients in the ED. This study aims to analyze the variability in the use of CT in mild TBI in Italian EDs, validate the scores designed to help the physician decide when to use it and develop a model that predicts the medium-term outcome of patients with mild head trauma.

Official title: The Use of Brain Computed Tomography in the Management of the Patient With Mild TBI in the Emergency Department

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

2500

Start Date

2026-01-21

Completion Date

2027-08-31

Last Updated

2026-05-20

Healthy Volunteers

No

Locations (24)

AOU Ospedale Civile SS.Antonio e Biagio

Alessandria, Italy

Ospedale San Bassiano

Bassano del Grappa, Italy

Ospedale Bentivoglio

Bentivoglio, Italy

Ospedale degli Infermi

Biella, Italy

Ospedale Maggiore "CA Pizzardi"

Bologna, Italy

Spedali Civili

Brescia, Italy

Ospedale Unico della Versilia

Camaiore, Italy

AOU Policlinico San Marco-PO Gaspare Rodolico

Catania, Italy

Ospedale Carlo Poma

Mantua, Italy

ASST Ca' Granda Niguarda

Milan, Italy

ASST Fatebenefratelli Sacco, P.O. Luigi Sacco

Milan, Italy

Policlinico di Milano Ospedale Maggiore

Milan, Italy

AOU San Luigi Gonzaga

Orbassano, Italy

Ospedale E. Agnelli Pinerolo

Pinerolo, Italy

Ospedale Santa Maria delle Croci

Ravenna, Italy

Ospedale degli Infermi

Rivoli, Italy

Istituto Clinico Humanitas

Rozzano, Italy

Ospedale Madonna del Soccorso

San Benedetto del Tronto, Italy

Humanitas Gradenigo

Torino, Italy

Ospedale San Giovanni Bosco

Torino, Italy

Ospedale Ca' Foncello

Treviso, Italy

Ospedale Michele e Pietro Ferrero

Verduno, Italy

Ospedale Civile

Voghera, Italy

Ente Ospedaliero Cantonale

Lugano, Switzerland