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Mild TBI in the Emergency Department
Sponsor: Mario Negri Institute for Pharmacological Research
Summary
Mild TBI is one of the main causes of admission to the Emergency Department (ED). Brain computed tomography (CT) is one of the most widely used diagnostic tools to assess the presence of intracranial lesions. However, in Western countries, 85-95% of CT scans performed in the ED for mild TBI are negative. It is therefore conceivable that a significant number of CTs could be avoided by a more careful use of this exam. On the other hand, excessive use of CT exposes patients to unnecessary radiation, increases healthcare costs and slows down the management of patients in the ED. This study aims to analyze the variability in the use of CT in mild TBI in Italian EDs, validate the scores designed to help the physician decide when to use it and develop a model that predicts the medium-term outcome of patients with mild head trauma.
Official title: The Use of Brain Computed Tomography in the Management of the Patient With Mild TBI in the Emergency Department
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2500
Start Date
2026-01-21
Completion Date
2027-08-31
Last Updated
2026-05-20
Healthy Volunteers
No
Conditions
Locations (24)
AOU Ospedale Civile SS.Antonio e Biagio
Alessandria, Italy
Ospedale San Bassiano
Bassano del Grappa, Italy
Ospedale Bentivoglio
Bentivoglio, Italy
Ospedale degli Infermi
Biella, Italy
Ospedale Maggiore "CA Pizzardi"
Bologna, Italy
Spedali Civili
Brescia, Italy
Ospedale Unico della Versilia
Camaiore, Italy
AOU Policlinico San Marco-PO Gaspare Rodolico
Catania, Italy
Ospedale Carlo Poma
Mantua, Italy
ASST Ca' Granda Niguarda
Milan, Italy
ASST Fatebenefratelli Sacco, P.O. Luigi Sacco
Milan, Italy
Policlinico di Milano Ospedale Maggiore
Milan, Italy
AOU San Luigi Gonzaga
Orbassano, Italy
Ospedale E. Agnelli Pinerolo
Pinerolo, Italy
Ospedale Santa Maria delle Croci
Ravenna, Italy
Ospedale degli Infermi
Rivoli, Italy
Istituto Clinico Humanitas
Rozzano, Italy
Ospedale Madonna del Soccorso
San Benedetto del Tronto, Italy
Humanitas Gradenigo
Torino, Italy
Ospedale San Giovanni Bosco
Torino, Italy
Ospedale Ca' Foncello
Treviso, Italy
Ospedale Michele e Pietro Ferrero
Verduno, Italy
Ospedale Civile
Voghera, Italy
Ente Ospedaliero Cantonale
Lugano, Switzerland