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INCIDENCE, PREVALENCE AND OVERALL RISK OF ESOPHAGEAL CANCER IN ACHALASIA: A PROPENSITY-MATCHED POPULATION-BASED STUDY FROM A LARGE MULTICENTER DATABASE
Sponsor: IRCCS San Raffaele
Summary
Esophageal Achalasia has been investigated as a potential risk factor for esophageal cancer (EC). Longstanding disease, repeated treatment, age and male sex seem the most relevant risk factors, but no clear effect size estimation from large sample cohorts has been provided so far. The aim of the investigators is to estimate EC risk in large sample-size population, and to provide sub-analyses per cancer type and treatment impact on EC risk.
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
47000
Start Date
2025-06-03
Completion Date
2025-09-07
Last Updated
2025-07-30
Healthy Volunteers
Yes
Conditions
Interventions
achalasia treatments
esophageal achalasia treatments
Locations (1)
IRCCS San Raffaele Hospital
Milan, Lombardy, Italy