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ACTIVE NOT RECRUITING
NCT07022886

INCIDENCE, PREVALENCE AND OVERALL RISK OF ESOPHAGEAL CANCER IN ACHALASIA: A PROPENSITY-MATCHED POPULATION-BASED STUDY FROM A LARGE MULTICENTER DATABASE

Sponsor: IRCCS San Raffaele

View on ClinicalTrials.gov

Summary

Esophageal Achalasia has been investigated as a potential risk factor for esophageal cancer (EC). Longstanding disease, repeated treatment, age and male sex seem the most relevant risk factors, but no clear effect size estimation from large sample cohorts has been provided so far. The aim of the investigators is to estimate EC risk in large sample-size population, and to provide sub-analyses per cancer type and treatment impact on EC risk.

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

47000

Start Date

2025-06-03

Completion Date

2025-09-07

Last Updated

2025-07-30

Healthy Volunteers

Yes

Interventions

PROCEDURE

achalasia treatments

esophageal achalasia treatments

Locations (1)

IRCCS San Raffaele Hospital

Milan, Lombardy, Italy